An observational study to optimize first-line treatment for human papilloma virus-related oropharyngeal carcinoma recorded in the Head and Neck Cancer Registry of Japan

An observational study to optimize first-line treatment for human papilloma virus-related oropharyngeal carcinoma recorded in the Head and Neck Cancer Registry of Japan - An observational study for human papilloma virus-related oropharyngeal carcinoma recorded in the Head and Neck Cancer Registry of Japan

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000035093

Enrollment

636

Registered

2018-12-01

Start date

2018-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HPV related oropharyngeal carcinoma

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Presence of primary oropharyngeal neoplasm. The neoplasm is pathologically confirmed as squamous cell carcinoma (SCC). Histopathologically confirmed 75 % or more of the cancer tissue is p16-positive by immunostaining, irrespective of the assessment time. Consent to participate in the present trial is obtained at the time of enrollment. Patients with oropharyngeal cancer registered after 2011 in the multicenter cancer registry of Japan.

Exclusion criteria

Exclusion criteria: History of treatment for head and neck cancer. Presence of active double cancer (synchronous double cancer, or metachronous double cancer with disease-free period of less than five years. However, lesions corresponding to carcinoma in situ, and mucosal carcinoma judged as cured by localized treatment will not be included as active double cancer) When the attending physician judges participation in the present study to be unsuitable.

Design outcomes

Primary

Measure	Time frame
Overall survival period	—

Secondary

Measure	Time frame
Local progression-free survival period Progression-free survival period Proportion of nutritional support-free survival	—

Countries

Japan

Contacts

Public ContactKatsunari Yane

Nara Hospital Kindai University Faculty of Medicine Otorhinolaryngology

kyane@med.kindai.ac.jp0743-77-0880

Outcome results