Effect of L-citrulline intake on exercise performance and fatigue in student athletes

Effect of L-citrulline intake on exercise performance and fatigue in student athletes - Effect of L-citrulline intake on exercise performance

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000035049

Enrollment

Registered

2018-11-28

Start date

2016-08-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Interventions

1) blood sampling, heart rate and blood pressure measurement before exercise 2) short-time high-intensity exercise (Wingate test) 3) blood lactic acid and RPE measurement during exercise 4) blood s

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Japanese healthy male students at Kanazawa University who were members of the university track team and specialized mainly in middle-distance running participated

Exclusion criteria

Exclusion criteria: participants who take nutritional supplements containing L-citrulline, Arginine, ornithine, glutamine, creatine, and branched chain amino acids (BCAA) regularly, or ingest large quantities of watermelon or other types of melon for the duration of the experiment

Design outcomes

Primary

Measure	Time frame
power output by bicycle ergometer, rate of perceived exertion, and amount of nitric oxide in blood after L-citrulline intake for 7 days	—

Secondary

Measure	Time frame
VO2, VCO2, carbohydrate oxidation, Fat oxidation, heart rate, blood pressure, lactic acid, white blood cell count, red blood cell count, hemoglobin, hematocrit, creatine phosphokinase, serum glucose, ammonia	—

Countries

Japan

Contacts

Public ContactNaoko Terasawa

Kanazawa University Faculty of Human Science

terasawa@staff.kanazawa-u.ac.jp076-264-5484

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026