Colorectal Cancer
Conditions
Interventions
None listed
Sponsors
ONO PHARMACEUTICAL CO., LTD.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who satisfy all the following items are included 1) Patients diagnosed with progressive colorectal cancer that cannot be resected radically 2) Patients who were measured body weight periodically at the time of visit and during the subsequent medical consultation period 3) Received cancer chemotherapy during the study period
Exclusion criteria
Exclusion criteria: Patients who meet at least one of the following exclusion criteria are not included. 1) Patients who underwent surgical operation of the gastrointestinal tract within the last 6 months, excluding colostomy and stent placement in the gastrointestinal tract 2) Patients with weight loss distinctly caused by a gastrointestinal transit disorder 3) Patients with simultaneously active, double cancer (Stage I intraepithelial carcinoma, intramucosal carcinoma, superficial bladder carcinoma, or other cancers without recurrence for 5 years or more can be registered) 4) Patients with missing of weight data over 12 weeks at the time of visit and during the subsequent medical consultation period 5) Patients who underwent puncture for ascitic fluid at the beginning of initial systemic chemotherapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The frequency of onset and the time to onset of cancer cachexia in patients who were diagnosed with unresectable advanced colorectal cancer for the first time and underwent systemic chemotherapy | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Relationship between onset of cancer cachexia and changes in laboratory parameter 2) Relationship between cancer cachexia and overall survival 3) Relationship between cancer cachexia and the continuation rate of anticancer chemotherapy 4) Relationship between cancer cachexia and the introduction rate of secondary therapy 5) Relationship between onset of cancer cachexia and introduction rate of tertiary therapy 6) Relationship between cancer cachexia and severity and incidence of anorexia and fatigue 7) Correlation between the changes in body weight of >= 5% (or if BMI < 20, changes in body weight of >2%) and changes in each laboratory parameter during the first systemic chemotherapy period at 12-week intervals evaluated from the beginning day of the first systemic chemotherapy | — |
Countries
Japan
Contacts
Public ContactSatoshi Hamauchi
Shizuoka Cancer Center Division of Gastrointestinal Oncology
Outcome results
None listed