None (Healthy adults)
Conditions
Interventions
Measurements of [15O]H2O-PET and [11C]Raclopride-PET during with/without head restraint. Measurements of physiological and psychological stress responses before, during and after PET scan.
Sponsors
Hamamatsu Photonics K.K.
Hamamatsu Medical Photonics Foundation.
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Individuals without a neurological or psychiatric history 2. Aged 20 to 60 years 3. Right-handed 4. Male 5. Capability of informed consent based on their own decision
Exclusion criteria
Exclusion criteria: 1.People with a history of traumatic brain injury and a episode of an unconsciousness lasting more than 5 minutes 2.People with a history of organic brain diseases 3. Individuals with a history or current history of substance dependence 4. Individuals who are taking central nervous system stimulants 5. Individuals who have a history of disorders of consciousness and/or seizure 6. Individuals who have a chronic headache 7. Individuals who are unable to undergo MRI
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Head restraint-induced changes of PET data | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Physiological stress responses 2. Psychological stress responses 3. Performances in cognitive tasks 4. Correlation between stress responses and PET data 5. Differences among stress responses before, durnig, and after PET scannings 6. Correlation between head movements and PET data | — |
Countries
Japan
Contacts
Public ContactTomoo Inubushi
Hamamatsu Photonics K.K. PET Medical Application Group, Central Research Laboratory
Outcome results
None listed