CKD stage 4 patients
Conditions
Interventions
Regarding aerobic exercise, patients in the exercise group are asked to perform unsupervised walking thrice weekly for 6 months. The target training zone was set at 40-60% of the peak heart rate, as d
Sponsors
Division of Endocrinology, Metabolism and Nephrology Department of Internal Medicine Keio University, School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with CKD stages 4 (estimated glomerular filtration rate,15-29 mL/min/1.73 m2)
Exclusion criteria
Exclusion criteria: The exclusion criteria were as follows: uncontrolled hypertension (blood pressure [BP] >180/110 mmHg), severe anemia (hemoglobin level <7 mg/dL), active and proliferative diabetic retinopathy, symptomatic coronary artery disease or cerebrovascular disease within 3 months before study recruitment, current heart failure (New York Heart Association classes III and IV), symptomatic and fatal arrhythmia, significant valvular heart disease, and difficulty walking without a walking aid owing to orthopedic problems, a history of cerebrovascular disease, or a history of peripheral artery disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Exercise capacity assessed by incremental shuttle walking test and quality of life, evaluated 6 months after assignment | — |
Secondary
| Measure | Time frame |
|---|---|
| Parameters including renal function, arterial stiffness, body composition, grip and quadriceps strength evaluated 6 months after assignment Cross-sectional association between exercise capacity and other parameters including HRQOL | — |
Countries
Japan
Contacts
Public ContactKiyotaka Uchiyama
Department of internal medicine, Keio University, School of Medicine Division of Endocrinology, Metabolism and Nephrology
Outcome results
None listed