metastatic liver tumor
Conditions
Interventions
sevoflurane arm permits only use of sevoflurane for maintenance of anesthesia.
propoforl arm permits only use of propofol for maintenance of anesthesia.
Sponsors
National Cancer Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. elective resection for metastatic liver tumor( including suspect of metastatic tumor) from any primary tumor, and estimated number of these tumors is 5 or under, and resection size is under Couinaud 5 area. 2. preoperative values of aspartate aminotransferase and alanine aminotransferase are both under 100 IU/L. 3. NOT scheduling primary tumor resection and/of radiofrequency ablation at the same time as liver resection. 4.NOT scheduling biliary reconstruction at the same time as liver resection. 5. obtained written infromed consent from patient.
Exclusion criteria
Exclusion criteria: 1. known allergy of study drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| max value of the aspartate aminotransferase during postoperative 3 days | — |
Secondary
| Measure | Time frame |
|---|---|
| max value of the alanine transaminase and total bilirubin during postoperative 3 days and postoperative complication defined by JCOG postoperative complication criteria according to Clavien-Dindo Classification grade 2 or more. | — |
Countries
Japan
Contacts
Public ContactJunya Matsumi
National Cancer Center Hospital Department of Anesthesia and Intensive Care
Outcome results
None listed