Verification of muscle strengthening effect of Neuromuscular electrical stimulation using wearable small electric stimulation device in patients with stable COPD: randomized controlled trials

Verification of muscle strengthening effect of Neuromuscular electrical stimulation using wearable small electric stimulation device in patients with stable COPD: randomized controlled trials - SIXPAD STUDY

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000034790

Enrollment

Registered

2018-11-07

Start date

2019-01-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic obstructive pulmonary disease

Interventions

Neuromuscular electric stimulation is warmed up for 3 minutes, stimulation for 20 minutes (setting of electrical stimulation is a symmetrical biphasic rectangular pulse current of 20 Hz, the pulse wid

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: A patient who has visited a respiratory center with COPD and has been able to continue rehabilitation for 8 weeks in hospital or outpatient at the discretion of a doctor. Diagnostic criteria for COPD are in accordance with 2017 GOLD.

Exclusion criteria

Exclusion criteria: Patients with central and peripheral neuropathy, progressive cancer, using cardiac pacemakers, contraindicated for cardiopulmonary exercise test

Design outcomes

Primary

Measure	Time frame
The primary endpoint is fat free mass index, and it is investigated before intervention 8 week and 6 months.	—

Secondary

Measure	Time frame
The secondary endpoint is fat free mass index, right upper limb muscle mass, left upper limb muscle mass, right lower limb muscle mass, left lower limb muscle mass, total muscle mass,% VC,% FEV1,FEV 1%,% FVC, step, METs, MVPA,6 minutes walking distance,WBI, grip, walking speed (m / sec), right upper limb circumference, left upper limb circumference, right circumference of right leg, left lower limb circumference, body weight,BMI, NRADL, CAT, m-MRC are investigated before intervention 8 weeks and 6 months.	—

Measure

Time frame

The secondary endpoint is fat free mass index, right upper limb muscle mass, left upper limb muscle mass, right lower limb muscle mass, left lower limb muscle mass, total muscle mass,% VC,% FEV1,FEV 1%,% FVC, step, METs, MVPA,6 minutes walking distance,WBI, grip, walking speed (m / sec), right upper limb circumference, left upper limb circumference, right circumference of right leg, left lower limb circumference, body weight,BMI, NRADL, CAT, m-MRC are investigated before intervention 8 weeks and 6 months.

—

Countries

Japan

Contacts

Public ContactHiroyuki Takemura

Matsusaka Municipal Hospital Department of Rehabilitation

pthiroyuki1988@gmail.com0598-23-1515

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026