The effect of dentifrice component on blood flow promoting in gingiva

The effect of dentifrice component on blood flow promoting in gingiva - The effect of dentifrice component on blood flow promoting in gingiva

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000034774

Enrollment

Registered

2018-11-10

Start date

2019-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

periodontitis

Interventions

Tooth brushing with dentifrice containing blood flow promoting component for 7days Tooth brushing with placebo dentifrice for 7days

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients of Periodontics in Dental Hospital of Tokyo Medical and Dental University 2. 20 years and over

Exclusion criteria

Exclusion criteria: 1. Patients suffering from infectious diseases such as hepatitis B, hepatitis C and HIV

Design outcomes

Primary

Measure	Time frame
Changes in the color of cervical gingiva (before treatment, after using VEN containing dentifrice and placebo dentifrice)	—

Secondary

Measure	Time frame
1. gingival index (GI) 2. plaque index (PI) 3. amount of VEFG and PGE2 in gingival crecivular fluid (befoe treatment, after using VEN containing dentifrice and placebo dentifrice)	—

Countries

Japan

Contacts

Public Contactkoji Koji Mizutani

Tokyo Medical and Dental University Department of Peridonotology

mizuperi@tmd.ac.jp0358035488

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026