sensorineural hearing loss
Conditions
Interventions
Intervention period (12 weeks), mount of intervention food (honeybee larvae 180mg x 4 tablets/day
Intervention period (12 weeks), placebo 4 tablets/day
Sponsors
Gifu Univesity School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. no perforation of the drum 2. mild bilateral sensorineural hearing loss (26-40dB) or moderate bilateral sensorineural hearing loss (41-60 dB) 3. subjective tinnitus of unilateral or bilateral ear 4. well understand the objective of this study
Exclusion criteria
Exclusion criteria: 1. subjects who already have had honeybee larave 2. active ottis media 3. acute hearing loss 4. apparent inner ear disease such as Meniere's disease 5. subjects who have received the treatment for hearing loss 6. allergy of the food 7. digestive dysfucntion of the honeybee larave products 8. cerebral vascular disease 9. blood donor within these 4 weeks 10. alcohol or drug dependence syndrome 11. subjects who had attended another clinical trial within 3 months 12. subjects living with teh house mate who attend this study 13. subjects who do not comply the rulr of this study 14. subject who are pointed out as nscreened personnel
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change of the hearing level on audiometry | — |
Secondary
| Measure | Time frame |
|---|---|
| Hearing Handicap Inventory for elderly,,Geriatric depression score,Chalder fatigue scale,, speech discrimination under noise, blood findings(IL2R, IL6,IL12,HDLC,LDLC,oxidative LDL,NO,DHEAS,HbA1c,adiponectine,SIRT1/3,Cre,UA,eGF,S1P) | — |
Countries
Japan
Contacts
Public ContactMitsuhiro Aoki
GIfu university Hospital Department of Otolaryngology
Outcome results
None listed