Analysis of the effect of periodontal infectious disease on response to biological disease-modifying antirheumatic drug in patients with rheumatoid arthritis.

Analysis of the effect of periodontal infectious disease on response to biological disease-modifying antirheumatic drug in patients with rheumatoid arthritis. - Analysis of the effect of periodontal infectious disease on response to biological disease-modifying antirheumatic drug in patients with rheumatoid arthritis.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000034665

Enrollment

Registered

2018-11-01

Start date

2018-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontal disease, Rheumatoid arthritis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with rheumatoid arthritis and periodontal disease.

Exclusion criteria

Exclusion criteria: Having less than 15 teeth, the presenc e of pregnancy, history or the presence of any periodontal and antibiotic treatment within the previous 3 months.

Design outcomes

Primary

Measure	Time frame
Disease activity score including 28 joints (DAS28) after 6 months of medication.	—

Secondary

Measure	Time frame
Tender joint count (TJC), Swollen joint count (SJC), and visual analogue scale (VAS) after 6 months of medication.	—

Countries

Japan

Contacts

Public ContactTetsuo Kobayashi

Niigata University Medical and Dental Hospital General Dentistry and Clinical Education Unit

kotetsuo@dent.niigata-u.ac.jp025-227-2870

Outcome results