Retrospective study comparing radiofrequency ablation and proton beam therapy for treatment naive solitary hepatocellular carcinoma: a propensity score analysis

Retrospective study comparing radiofrequency ablation and proton beam therapy for treatment naive solitary hepatocellular carcinoma: a propensity score analysis - HCC RFA-Proton

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000034661

Enrollment

100

Registered

2018-11-01

Start date

2018-09-12

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hepatocellular carcinoma

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Histologically or clinically diagnosed primary hepatocellular carcinoma. Untreated and absence of previous local therapy. 2) Absence of vascular invasion. 3) ECOG PS: 0-2. 4) Child-Pugh score of the patient is from 5 points to 8 points. 5) The tumor is measurable and tumor size is less than 5 cm. 6) Solitary tumor

Exclusion criteria

Exclusion criteria: 1) Having extrahepatic lesions. 2) Previously treated with percutaneous ethanol injection therapy 3) Total bilirubin is more than 3.0 mg/dL

Design outcomes

Primary

Measure	Time frame
Overall survival (Five-year overall survival rate)	—

Secondary

Measure	Time frame
Local control period (Five-year Local control rate), progression free survival (Five-year progression free survival rate), Adverse event	—

Countries

Japan

Contacts

Public ContactToshiyuki Okumura

University of Tsukuba Dept. of Radiation Oncology, Faculty of Medicine

okumura@pmrc.tsukuba.ac.jp029-853-7100

Outcome results