Food Allergy
Conditions
Interventions
None listed
Sponsors
National Center for Child Health and Development
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)children who planning to undergo OFC of egg, milk, and wheat. 2)5-15 years old 3)Children who can autonomously urinate 4)Children who can appeal around the oral symptom 5)Cases with consent 6)Children in which allergic diseases are controlled such as bronchial asthma, atopic dermatitis, allergic rhinitis
Exclusion criteria
Exclusion criteria: 1) Children taking medications affecting PGDM such as NSAIDs. 2) Children taking medicines within 3 days, such as anti-His drugs, anti-leukotriene receptor antagonists, etc., which affect the evaluation of the OFC. 3) Parents can not understand Japanese. 4) Children with severe complications. 5) Other children who thought the doctor was inappropriate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlation between Prostaglandin D Metabolite in urine 4 hours after ingestion of food and result of double blind placebo-controlled food challenge test. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Correlation between Prostaglandin D2 in saliva and result of double blind placebo-controlled food challenge test. 2)Correlation between Prostaglandin D Metabolite in urine 2,4,6 hours after ingestion of food and result of double blind placebo-controlled food challenge test. | — |
Countries
Japan
Contacts
Public ContactYusuke Inuzuka
National Center for Child Health and Development Allergy Center
Outcome results
None listed