Effects of perioperative administration of synthetic steroid on glycometabolism and insulin resistance

Effects of perioperative administration of synthetic steroid on glycometabolism and insulin resistance - Effects of perioperative administration of synthetic steroid on glycometabolism and insulin resistance

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000034634

Enrollment

Registered

2018-10-25

Start date

2018-10-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

preoperative management for oral, maxirofacial surgery and dental surgery

Interventions

Synthetic steroid Normal saline

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: written informed concent is obtained from patients who undergo oral surgery aged from 20 to 50 ASA from 1 or 2 estimated operation time:3-7 hours

Exclusion criteria

Exclusion criteria: patients diagnosed with diabetes mellitus or disorder of carbohydrate metabolism 18.0>BMI BMI<=30 patients to who should not receive rinderon patients whom reseachers consider inappropriate

Design outcomes

Primary

Measure	Time frame
Postoperative Insulin Resistance	—

Secondary

Measure	Time frame
change of blood glucose nduring general anesthesia, blood test (lactate, free fatty acid,ketone body, catecholamine, 3-methylhistidine(indicator of muscle protein degradation,cortisol), serum electrolyte(Na+,K,Mg2+,Ca2+,Cl-),arterial blood gas (pH,PaCO2,PaO2,HCO3-,BE),urine glucose, urea nitrogen	—

Countries

Japan

Contacts

Public ContactSayuri Kadowaki

Kyushu University Hospital Department of Dental Anesthesiology

s.koyama@dent.kyushu-u.ac.jp0926426480

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026