Healthy adults
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Healthy male panelists who are 20-49 years old. 2.Healthy female panelists who are 20-49 years old and have regular menstruation. 3.Panelists who agree to have their typical daily routines.
Exclusion criteria
Exclusion criteria: 1.Panelists who have irregular menstruation or who experience menopause. 2.Panelists who has become pregnant and breast-feeding. In addition, panelists who have possibility of pregnant during the study period. 3.Panelists who have the skin problems on the face, such as atopic dermatitis, psoriasis vulgaris, and acnes. 4.Panelists who have a severe tanning on the face. 5.Panelists who smoke. 6.Panelists who use the drug such as, anti-inflammatory drug, antibiotics, hypnotic, anti- allergic drug, analgesic drug, hormone preparation, laxative, intestinal regulator, and other drugs as routinely. 7.Panelists who attend for treatment of chronic diseases (e.g. stomach, intestine, kidney, heart, blood pressure, skin, and other illness) or have history of attending within a month before participation in this study (Manual therapy, chiropractic, massages, and osteopathic manipulation are exceptional). 8.Panelists who attend cosmetic therapy (e.g. chemical peeling, laser therapy) or have history of cosmetic surgery (e.g. cosmetic orthopedics, collagen injection). 9.Male panelists who randomly shave during the study period. Female panelists who randomly remove downy hairs on their face during the study period. 10.Panelists who have participated or scheduled in other study during the study period. 11.Panelists who is considered as inappropriate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The variations of skin molecules in the day and from day to day. | — |
Secondary
| Measure | Time frame |
|---|---|
| -The relationship between skin molecules and questionnaires. -The evaluation of regional differences of skin molecules between face and scalp. | — |
Countries
Japan
Contacts
Kao Corporation Biological Science Research