normal subjects
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients not using contact lenses. 2.Patients who had ocular surgery before the last six months. 3.patients who understands the contents of the consent document and is able to consent in the document of the person.
Exclusion criteria
Exclusion criteria: 1.Patients who have any disease. conjunctival injection dry eye symptoms corneal epithelial damage 2.Patients who take current medications during the past one month . 3.Patients using contact lenses. 4.Patients judged by other research managers or researchers as inappropriate to implement this research safely.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mRNA expressions of MUC5AC and MUC16 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Dry Eye-related Quality of life Score (DEQS) 2.Tear film break-up time(BUT) 3.Corneal epithelial damage 4.Microflora analysis | — |
Countries
Japan
Contacts
Tsurumi University School of Dental Medicine Department of Ophthalmology