Comparison of the plasma levobupivacaine concentrations with and without epinephrine after ultrasound-guided erector spinae plane block

Comparison of the plasma levobupivacaine concentrations with and without epinephrine after ultrasound-guided erector spinae plane block - Comparison of the plasma levobupivacaine concentrations with and without epinephrine after ultrasound-guided erector spinae plane block

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000034479

Enrollment

Registered

2018-10-14

Start date

2018-06-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast surgery

Interventions

Ultrasound-guided erector spinae plane block will be performed using 2mg/kg levobupivacaine. Ultrasound-guided erector spinae plane block will be performed using 2mg/kg levobupivacaine with 5microg/ml

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Elective breast surgery is scheduled. 2) Written informed consent for ultrasound-guided erector spinae plane block is obtained. 3) American Society of Anesthesiologists physical status is either 1, 2, or 3.

Exclusion criteria

Exclusion criteria: 1) Local anesthetic allergy 2) Coagulation abnormality 3) Liver dysfunction (child-pugh score is B or C) 4) Renal dysfunction (eGFR<60) 5) Contraindication to epinephrine

Design outcomes

Primary

Measure	Time frame
The serum time course of the levobupivacaine concentration	—

Countries

Japan

Contacts

Public ContactHiroe Shigeta

National hospital organization Tokyo medical center Anesthesiology

hiroe_y_0614@hotmail.co.jp03-3411-0111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026