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Effect of pregabalin on neuropathic pain in Yusho patients: open label pilot study

Effect of pregabalin on neuropathic pain in Yusho patients: open label pilot study - Effect of pregabalin on neuropathic pain in Yusho patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000034468
Enrollment
20
Registered
2018-11-01
Start date
2018-12-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Yusho

Interventions

For the symptoms of numbness and sensation deterioration in Yusho patients, pregabalin 25 mg is orally administered for 4 weeks and the effect judgment is carried out and the result is analyzed. In ad

Sponsors

Nagasaki University Hospital Dermatology / Allergy Department
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who satisfy all the following criteria are targeted. 1.Age: patients aged 50 or older at the time of acquisition 2.Gender: No prejudice 3.Hospitalization / Outpatient: Outpatient only 4.After receiving sufficient explanation for participation in this study, patients who obtained document consent by the patient's free will with sufficient understanding. 5.Patient who is untreated for abnormal sensation of limbs or patient who is inadequate in current symptomatic treatment.

Exclusion criteria

Exclusion criteria: Patients applicable to even one of the following are excluded as subjects. 1.Patient currently taking pregabalin 2.Patients with serious liver and kidney dysfunction 3.Patients with drug hypersensitivity such as allergy to pregabalin 4.In addition, patients whose research managers judged inappropriate as research subjects

Design outcomes

Primary

MeasureTime frame
The effect of pregabalin on sensory disorders such as numbness of the subjects is compared for each of VAS, Von frey, and heat sensation for each difference before pregabalin administration and at the end of administration (4th week after administration start).

Countries

Japan

Contacts

Public ContactYoshiyuki Kamio

Nagasaki University Hospital Dermatology / Allergy Department

y-kamio@nagasaki-u.ac.jp095-819-7333

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026