A research of the effect of mineral water consumption derived from Nagayu hot spring on prediabetes patients: a crossover study

A research of the effect of mineral water consumption derived from Nagayu hot spring on prediabetes patients: a crossover study - A research of the effect of mineral water consumption derived from Nagayu hot spring on prediabetes patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000034448

Enrollment

Registered

2018-10-11

Start date

2018-10-11

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prediabetes

Interventions

Group A: Consumption of control water for 14 days. Consumption of 500 ml of control water divided into thrice daily (30-60 minutes before breakfast, lunch, and dinner) Group B: Consumption of miner

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Subjects who show understanding of the study procedures and agreement with participating the study by written informed consent prior to the study. 2) Males and females who live in Taketa city. 3) Subjects whose HbA1c (NGSP) values are ranged from 5.6 to 6.4% in principle.

Exclusion criteria

Exclusion criteria: 1) Subjects who frequently consume medicine for diabetes. 2) Subjects who frequently consume mineral water that collected from Nagayu hot spring.

Design outcomes

Primary

Measure	Time frame
Clinical blood test (HbA1c, glycoalbumin, blood glucose and insulin)	—

Secondary

Measure	Time frame
- 16S metagenome analysis of gut microbiota - Metabolome analysis of intestinal metabolites - Gastrointestinal Symptom Rating Scale (GSRS), Japanese edition - Questionnaire - Body weight - Body Mass Index (BMI)	—

Countries

Japan

Contacts

Public ContactShinnosuke Murakami

Metabologenomics, Inc. Headquarters

clinical-trials@metagen.co.jp+81-235-64-0330

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Sep 19, 2026