Skin disorder caused by EGFR inhibitors
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Lung cancer patients with positive EGFR gene variation Patients receiving gefitinib(Iressa),erlotinib(Tarceva),afatinib(Giotrif),osimertinib(Tagrisso),Cetuximab(Erbitax),Panitumumab(Vectibix) Patients aged of 18 over at the time of enrollment The sex does not matter
Exclusion criteria
Exclusion criteria: Person who experienced skin symptoms such as contact dermatitis due to the ingredients of this research item and similar ingredients In addiction,parson who the research staff judged inappropriate as subjects
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the safety(5% or less rate of adverse effect) | — |
Secondary
| Measure | Time frame |
|---|---|
| Skin physiological verification(changes in skin measurement value and cytokine in epidermal horny layer) Changes in stratum corneum water content,epidermal water transpiration amount,sebum quantity Improvement of QOL and feeling of use of this research product by questionnaire | — |
Countries
Japan
Contacts
Osaka city University Hospital Dermatology