Effects of Blind Makeup Application in Persons with Impaired Vision: Brain Activity Evaluation by Functional Magnetic Resonance Imaging

Effects of Blind Makeup Application in Persons with Impaired Vision: Brain Activity Evaluation by Functional Magnetic Resonance Imaging - Effects of Blind Makeup Application in Persons with Impaired Vision: Brain Activity Evaluation by Functional Magnetic Resonance Imaging

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000034431

Enrollment

Registered

2018-10-10

Start date

2046-12-31

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Persons with Impaired Vision

Interventions

A preliminary test will be conducted in 6 right-handed women with normal vision. (1) After washing the face (natural face), the stimuli of (2) makeup activity through recollection and (3) actual makeu

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: - Women who use makeup daily - Subjects who are right-handed Persons who provide written consent (oral in the case of persons with vision impairment) of their own volition after receiving a sufficient explanation regarding participating in the study and sufficiently understanding that explanation. Note that if a subject has a disease other than a skin disease, treatment will not be restricted.

Exclusion criteria

Exclusion criteria: - Persons with severe skin disease on the face - Persons who have experienced skin symptoms such as contact dermatitis from the ingredients of the study drug or a similar ingredient - Persons who should avoid fMRI measurements (such as persons with implanted gold thread from cosmetic surgery) - Persons who use drugs that affect brain activity - Pregnant women - Other persons that the investigator deems unsuited to participate in this study

Design outcomes

Primary

Measure	Time frame
fMRI measurement (1)Measurement device An Ingenia 3.0T (manufactured by Philips) will be used. (2)Measurement methods (i)Advance screening A T2-weighted image will be obtained before the fMRI measurement to check that there is no organic disease such as cerebrovascular impairment in the cranium. (ii)Measurements will be taken when the subject has no facial makeup A facial cleanser (NOV III Cleansing Cream, NOV III Washing Cream) will be used to wash the face, and then a moisturizing agent (NOV III Face Lotion R) will be applied to eliminate any skin discomfort such as the sensation of dry skin. fMRI measurement will be performed 5 minutes later. iii) Measurements will be taken while the subject imagines makeup The radiological technician shall instruct the subject to imagine makeup tasks and will perform the measurement once the subject has done so. iv)Measurements will be taken after applying makeup The subject will step down from the measurement stand and apply makeup. Measurements shall be performed immediately after makeup is applied. (3)Measurement conditions The previously mentioned 3TMRI scanner will be used for imaging.The functional image will be obtained by gradient echo planar imaging (EPI), and the following parameters are to be set:repetition time (TR) = 3000 ms, echo time (TE) = 30 ms, flip angle = 90, matrix size = 94*94,field of view = 230 mm,size number = 45,slice thickness = 3 mm, interslice gap = 0 mm, acquisition time = 5:09 s.	—

Measure

Time frame

fMRI measurement (1)Measurement device An Ingenia 3.0T (manufactured by Philips) will be used. (2)Measurement methods (i)Advance screening A T2-weighted image will be obtained before the fMRI measurement to check that there is no organic disease such as cerebrovascular impairment in the cranium. (ii)Measurements will be taken when the subject has no facial makeup A facial cleanser (NOV III Cleansing Cream, NOV III Washing Cream) will be used to wash the face, and then a moisturizing agent (NOV III Face Lotion R) will be applied to eliminate any skin discomfort such as the sensation of dry skin. fMRI measurement will be performed 5 minutes later. iii) Measurements will be taken while the subject imagines makeup The radiological technician shall instruct the subject to imagine makeup tasks and will perform the measurement once the subject has done so. iv)Measurements will be taken after applying makeup The subject will step down from the measurement stand and apply makeup. Measurements shall be performed immediately after makeup is applied. (3)Measurement conditions The previously mentioned 3TMRI scanner will be used for imaging.The functional image will be obtained by gradient echo planar imaging (EPI), and the following parameters are to be set:repetition time (TR) = 3000 ms, echo time (TE) = 30 ms, flip angle = 90, matrix size = 94*94,field of view = 230 mm,size number = 45,slice thickness = 3 mm, interslice gap = 0 mm, acquisition time = 5:09 s.

—

Countries

Japan

Contacts

Public ContactHiroshi Matsunaka

TOKIWA Phormaceutical Co., Ltd. NOV Academic Research

yumi_murakami@n1.noevir.co.jp03-6634-5181

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026