Gastric cancer after H.pylori eradication
Conditions
Interventions
P.gingivalis LPS low concentration
P.gingivalis LPS high concentration
P.gingivalis LPS + Acetaldehyde low
P.gingivalis LPS + Acetaldehyde high
Sponsors
Tohoku University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: post-eradication GC lesions, which were newly discovered later than 24 months after successful eradication.
Exclusion criteria
Exclusion criteria: 1) patients younger than 20 years old or older than 85 years old; 2) patients with a history of chemotherapy, radiotherapy or upper abdominal surgery; 3) patients taking nonsteroidal anti-inflammatory drugs, antibiotics, or any acid secretion inhibitors; 4) patients with serious medical conditions; 5) patients suffering from mental disorders; 6) patients who might be pregnant; 7) patients with inappropriate specimens; 8) patients with contraindication for endoscopic biopsy or gastrin injection; and 9) patients who refused to participate in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mucosal damage of atrophic mucosa by the stimulation of P.gingivalis LPS or LPS and acetaldehyde | — |
Countries
Japan
Contacts
Public ContactKaname Uno
Tohoku University Hospital Division of Gastroenterology
Outcome results
None listed