Hepatocellular carcinoma
Conditions
Interventions
repeated alternate infusion of cisplatin and gelatin fragments for balloon-occluded trans-catheter arterial chemo-embolization for hepatocellular carcinomas.
Sponsors
University of Tsukuba
Mito Kyodo General Hospital Tsukuba Memorial Hospital Tsukuba Medical Center Hospital Japanese Red Cross Maebashi Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Diagnosis of hepatocellular carcinoma according to EASL guideline 2)Indication of TACE 3)over 20 year old and less 90 year old 4)ECOG Performance Status of 0 to 1 5)Informed consent is obtained. 6)promising over 3 month alive after treatment
Exclusion criteria
Exclusion criteria: 1)After rupture of HCC with shock vital 2)History of surgical or endoscopic biliary tract reconstruction 3)Dilation of segmental biliary tract 4)Lymph node metastases displacing biliary tract or portal vein 5)Prominent arterio-portal shunt or arterio-venous shunt 6)eGFR is under 50 ml/min/1.73m2 7)Child-Pugh score: over 7 score 8)History of TACE within 3 months in the area of therapeutic plan 9)Hepatic encephalopathy or severe psychic disturbance 10)Severe drug allergy including iodine contrast medium or other drugs 11)Inadequate patients to undergo the procedure safely 12) Tumor invades main or first branch of portal vein
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety of RAIB-TACE | — |
Secondary
| Measure | Time frame |
|---|---|
| Tumor response based on RECICL criteria | — |
Countries
Japan
Contacts
Public ContactSodai Hoshiai
University of Tsukuba Faculty of Medicine
Outcome results
None listed