Comparison of the tear level between (-)-epigallocatechin gallate (EGCG) and (-)-epigallocatechin 3-O-(3-O-methyl) gallate (EGCG3"Me) after oral administration in healthy volunteers.

Comparison of the tear level between (-)-epigallocatechin gallate (EGCG) and (-)-epigallocatechin 3-O-(3-O-methyl) gallate (EGCG3"Me) after oral administration in healthy volunteers. - Comparison of the tear level in green tea catechins after oral administration in healthy volunteers.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000034291

Enrollment

Registered

2019-03-31

Start date

2018-10-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

For the EGCG-containing tea treatment or EGCG3Me-containing tea treatment

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Japanese healthy adults

Exclusion criteria

Exclusion criteria: When an adverse event develops (including the accident). When we judge that a study responsibility physician or a study allotment physician should discontinue it. When a study is stopped on account of the subjects (moving, the pressure).

Design outcomes

Primary

Measure	Time frame
The tear level of pharmacokinetic parameter (AUC 0-24, Cmax) of EGCG and EGCG3Me after green tea administration.	—

Countries

Japan

Contacts

Public ContactNoriko Hida

ShowaUnivrsity Department of Pharmacology Clinical Pharmacology

n.hidada@med.showa-u.ac.jp03-3300-5254

Outcome results