Evaluation of aging changes of the magnetic susceptibility in the brain in healthy Japanese

Evaluation of aging changes of the magnetic susceptibility in the brain in healthy Japanese - Evaluation of the magnetic susceptibility in the brain in healthy Japanese

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000034287

Enrollment

249

Registered

2018-09-27

Start date

2017-03-08

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteers

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) >20 and <90 years old 2) informed consent is obtained after detailed explanation

Exclusion criteria

Exclusion criteria: 1) past history of central nervous system or neuropsychiatric disorder 2) metallic implant and other MRI contraindicated objects 3) claustrophobia 4) pregnant female (including possible case)

Design outcomes

Primary

Measure	Time frame
Correlation of the local magnetic susceptibility in quantitative susceptibility mapping (QSM) and age	—

Secondary

Measure	Time frame
1) Correlation of the localbrain atrophy using T1 weighted image (T1WI) and magnetic susceptibility in QSM 2) Correlation of the local cerebral blood flow in arterial spin labelling (ASL) and magnetic susceptibility in QSM 3) Correlation of the local diffusion parameters in diffusion tensor image (DTI) magnetic susceptibility in QSM 4) Correlation of the various types of imaging parameters in quantitative parametrical mapping (QPM) and magnetic susceptibility in QSM 5) Correlation of the result of cognitive function test (MMSE, MOCA-J) and magnetic susceptibility in QSM 6) Correlation of the magnetic susceptibility in QSM between MRI machines	—

Measure

Time frame

1) Correlation of the localbrain atrophy using T1 weighted image (T1WI) and magnetic susceptibility in QSM 2) Correlation of the local cerebral blood flow in arterial spin labelling (ASL) and magnetic susceptibility in QSM 3) Correlation of the local diffusion parameters in diffusion tensor image (DTI) magnetic susceptibility in QSM 4) Correlation of the various types of imaging parameters in quantitative parametrical mapping (QPM) and magnetic susceptibility in QSM 5) Correlation of the result of cognitive function test (MMSE, MOCA-J) and magnetic susceptibility in QSM 6) Correlation of the magnetic susceptibility in QSM between MRI machines

—

Countries

Japan

Contacts

Public ContactKudo Kohsuke

Hokkaido university hospital Department of Diagnostic and Interventional Radiology

kkudo@huhp.hokudai.ac.jp011-706-7779

Outcome results