Healthy adult
Conditions
Interventions
Low carbohydrate diet and the 50g placebo formula,3 times per day
Low carbohydrate diet and the 50g Ketonformula,3 times per day
Normal diet, 3 times per day
Sponsors
Department of Advanced Hybrid Medicine Graduate School of Medicine, Osaka University
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1) Subjects who have given written informed consent 2) Healthy males aged 20 to 40 years old 3) Subjects whose BMI is 18.5 to 25.0 4) Subjects whose height is 165 cm to 175 cm
Exclusion criteria
Exclusion criteria: 1) Subjects having a smoking habit 2) Subjects receiving drug treatment 3) Subjects whose blood test value are not within the standard values 4) Subjects with gastrointestinal complications 5) Food allergies 6) Lactose intolerance 7) Subjects undergoing carbohydrate restriction or ketogenic diet 8) Subjects who were collected over 400 mL blood within 3 months 9) Subjects who participated another clinical trials within 3 months 10) Any other person whom the principal investigator has determined to be unsuitable as a participant of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| plasma concentration of ketone bodies (acetoacetic acid, 3-hydroxybutyrate) | — |
Secondary
| Measure | Time frame |
|---|---|
| plasma concentration of acetoacetic acid plasma concentration of 3-hydroxybutyrate plasma concentration of medium chain fatty acids Acetone concentration in human breath | — |
Countries
Japan
Contacts
Public ContactKeisuke Hagihara
Graduate School of Medicine, Osaka University Department of Advanced Hybrid Medicine
Outcome results
None listed