Healthy adults
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Who have subjective symptoms of dry skin
Exclusion criteria
Exclusion criteria: 1. Who have any skin disease 2. Who have any serious illness, for example, heart disease, kidney disease, diabetes mellitus, and so on. 3. Who take any medicine which effect intestinal flora, such as antibiotics. 4. Who have allergic to apple, soy bean, dairy food. 5. Who expose to high-intensity ultraviolet rays. 6. Who are pregnant or breast-feeding or willing to be pregnant during this study. 7. Who have receive medical treatments for gastrointestinal diseases that affect regulation of intestinal function, or a history of those (except for appendicectomy). 8. Who have participated in other clinical study for skin during this study, or willing to be that. 9. Who are eating an unbalanced diet, such as binge eating, and fasting. 10, Who are judged unsuitable for this study by principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Water content of stratum corneum, and moisture transpiration. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Concentration of phenolic compound in feces. 2. Construction of fecal micro biota. | — |
Countries
Japan
Contacts
Kagome Co. Ltd. Nature & Wellness Research Department