A investigation of temperature maintenance effect by the intake of a anthocyanin-containing juice in adult male with feeling cold.

A investigation of temperature maintenance effect by the intake of a anthocyanin-containing juice in adult male with feeling cold. - A investigation of temperature maintenance effect by the intake of a anthocyanin-containing juice in adult male with feeling cold.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000034184

Enrollment

Registered

2018-09-20

Start date

2018-09-21

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adult

Interventions

Oral intake of a anthocyanin medium- containing juice (1 time) - washout period of week - Oral intake of a placebo juice (1 time) - washout period of week - Oral intake of a anthocyanin high - con

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: (1) Healthy males more than 20 years old. (2) Subjects who are sensitive to the cold and whose cold diagnosis questionnaire score is more than 4 points. (3) Subjects whose recovery rate of skin temperature is less than 90% after 10 minutes of cold loading. (4) Subjects who are obtained consent by document in free will.

Exclusion criteria

Exclusion criteria: (1)Subjects who have an allergy in connection with this study. (2) Subjects who have been diagnosed disease with vascular disorder (e.g., arteriosclerosis obliterans, obliterating arteritis, connective tissue disease, diabetes ). (3) Subjects who are judged as unsuitable for the study based on the results of medical questionnaire. (4) Subjects who have smoking habit. (5) Subjects who are regularly taking medicine (e.g., warfarin) which may influence skin surface temperature and blood flow. (6) Subjects who are taking health food, food for specified health use which may influence skin surface temperature and blood flow more than 3 times per week (e.g., functional food which assume polyphenol derived from ginger or hesperidin as active ingredient) . (7) Subjects who have taken anthocyanin enriched food more than 3 times per week. (8) Subjects who are judged as unsuitable for the study based on the results of clinical examination and cardiopulmonary function. (9) Subjects who have regular medication and a history of serious disease which needed medication treatment. (10)Subjects who are judged as unsuitable for the study based on the results of physical and clinical examination on before intake. (11)Subjects who have participated in other clinical study at the start of this study. (12)Subjects who are judged as unsuitable for the study by the investigator for other reason.

Design outcomes

Primary

Measure	Time frame
Skin surface temperature	—

Secondary

Measure	Time frame
Peripheral blood flow	—

Countries

Japan

Contacts

Public ContactKunihiko Wasaki

TTC Co.,Ltd. Clinical Research Planning Department

k.wasaki@ttc-tokyo.co.jp0354593714

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026