The effect of compression therapy using surgical gloves on (R-)CHOP therapy induced peripheral neuropathy(randomized control trial)

The effect of compression therapy using surgical gloves on (R-)CHOP therapy induced peripheral neuropathy(randomized control trial) - compression therapy (R-CHOP)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000034145

Enrollment

103

Registered

2018-11-01

Start date

2018-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

non-Hodgkin lymphoma

Interventions

For every vincristine infusion, each patients wear two Surgical groves of the same size on their dominant hand for only 100 min: during the 30 min before the administration of vincristine, during the

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients with untreated malignant lymphoma who receive (R-)CHOP therapy untreated malignant lymphoma porfomance status 0-2 patients who do not have latex allergy patients who got written informed consent

Exclusion criteria

Exclusion criteria: patients who treat stem cell transplantation for hematological malignancy

Design outcomes

Primary

Measure	Time frame
The incidence of (R-)CHOP induced peripheral neuropathy grade 2 or higher between the compression hand and control hand using the CTCAE version 4.0 at one month after treatment	—

Secondary

Measure	Time frame
The incidence of (R-)CHOP induced peripheral neuropathy grade 1 or higher between the compression hand and control hand using the CTCAE version 4.0 at following times:before each treatment cycle, and half year after treatment, and one year after treatment The incidence of (R-)CHOP induced peripheral neuropathy grade B or higher between the compression hand and control hand using the PNQ at following times :before each treatment cycle, and one month after treatment, half year after treatment, and one year after treatment withdraw from compression therapy	—

Measure

Time frame

The incidence of (R-)CHOP induced peripheral neuropathy grade 1 or higher between the compression hand and control hand using the CTCAE version 4.0 at following times:before each treatment cycle, and half year after treatment, and one year after treatment The incidence of (R-)CHOP induced peripheral neuropathy grade B or higher between the compression hand and control hand using the PNQ at following times :before each treatment cycle, and one month after treatment, half year after treatment, and one year after treatment withdraw from compression therapy

—

Countries

Japan

Contacts

Public ContactSuyama Takuya

Hitachi general hospital hematology,oncology

sutaku2468@yahoo.co.jp0294231111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026