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Comparative test of morphine hydrochloride internal solution and hydromorphone hydrochloride tablets on idiopathic dyspnea

Comparative test of morphine hydrochloride internal solution and hydromorphone hydrochloride tablets on idiopathic dyspnea - Comparative test of morphine hydrochloride internal solution and hydromorphone hydrochloride tablets on idiopathic dyspnea

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000034124
Enrollment
30
Registered
2018-09-14
Start date
2018-09-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Idiopathic dyspnea

Interventions

Morphine hydrochloride solution or hydromorphone hydrochloride tablet should be taken when the subject feels sudden breathing difficulty. As soon as subjects take either of them, subjects will be eval

Sponsors

Ashiya Municipal Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Over 18 years old 2.People who show exacerbation of dyspnea and exacerbation of uncomfortable feeling, which exceeds the range of dyspnea normally experienced by patients 3.Dyspnea intensities average on average Numeric rating scale (NRS) >= 3 4.Karnofsky Performance Status >= 50

Exclusion criteria

Exclusion criteria: 1.People who have a cognitive decline that can not be answered by survey forms 2.Patients with chronic obstructive pulmonary disease 3.Heart failure patients 4.Patients with severe renal impairment 5.Those receiving oxygen assistance above 6 L / min 6.Persons with drug abuse history

Design outcomes

Primary

MeasureTime frame
NRS for respiratory distress (45 minutes after administration)

Countries

Japan

Contacts

Public ContactNiki Kazuyuki

Osaka University/Ashiya Municipal Hospital Graduate School of Pharmaceutical Sciences/Department of Pharmacy

k-niki@phs.osaka-u.ac.jp06-6879-8250

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026