glaucoma
Conditions
Interventions
Group A receives the ophthalmic solution of Xalatan for 6 months once every day in both eyes at 21:00 +/- 2 hours.
Group B receives Latanoprost eye drop "
Nittens"
for 6 months once every day in both eyes at 21: 00 +/- 2 hours.
Sponsors
The University of Tokyo Hospital
Touto Bunkyo Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age: > 20 years and < 80 years, gender unquestioned 2. Confirmed diagnosis of open-angle glaucoma (broad sense) 3. The number of glaucoma ophthalmic medications in use shall be limited to one agent (regardless of type) 4. Experience of taking Humphrey visual field 5. Fixation failure, false positive, and false negative rate which are targets for reliability of visual field are all less than 20% 6. The mean deviation (MD) value of the visual field is > -10 dB 7. Spherical equivalent is > -6.0 diopters and corrected visual acuity is > 1.0
Exclusion criteria
Exclusion criteria: 1. With a history of eye surgery including laser 2. Having allergy to prostaglandin related drug 3. Using ophthalmic or internal steroids 4. Oral administration of acetazolamide (Diamox) 5. The contact lenses are scheduled to be used during the test period 6. Persons who judged that the doctor in charge is not appropriate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of intraocular pressure lowering effect for 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Time course of conjunctival hyperemia and corneal epithelial disorder for 6 months | — |
Countries
Japan
Contacts
Public ContactRei Sakata
The University of Tokyo Hospital Department of ophthalmology
Outcome results
None listed