Depression
Conditions
Interventions
None listed
Sponsors
Showa University School of Medicine Department of Psychiatry
Keio University School of Medicine Institute for Advanced Biosciences, Keio University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with depression Age above 60 years old at the time of agreement. Patients with depression admitted to the Showa University Karasuyama Hospital or the Keio University Hospital. Healthy participants Elders who are willing to participate in this study without the history of psychiatric disorders. Age above 60 years old at the time of agreement.
Exclusion criteria
Exclusion criteria: Participants with dementia. Participants with gastrointestinal disorder. Participants who are receiving the antibiotic treatment. Participants who can not agree with collecting faces samples or with taking the brain MRI.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Feces samples will be collected at least three times during a month period. Bacterial metagenome and metabolomics will be assessed with 16SrRNA methodology and Mass spectrometry. | — |
Secondary
| Measure | Time frame |
|---|---|
| Original questionnaire of lifestyles Brief-type self-administered Diet History Questionnaire Hamilton Depression Rating Scale Hamilton Anxiety Scale Montgomery-Asberg Depression Rating Scale Pittsburgh Sleep Quality Index Gastrointestinal Symptom Rating Scale Original questionnaire of Gastro- intestinal Symptom fMRI | — |
Countries
Japan
Contacts
Public ContactKatsuma Miyaho
Showa University School of Medicine Department of Psychiatry
Outcome results
None listed