Effect of peripheral nerve block on post-operative delirium and post-operative cognitive dysfunction following total hip arthroplasty in elderly patients.

Effect of peripheral nerve block on post-operative delirium and post-operative cognitive dysfunction following total hip arthroplasty in elderly patients. - Effect of PNB on POD and POCD following total hip arthroplasty in elderly patients.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000034071

Enrollment

Registered

2018-09-09

Start date

2018-09-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients aged over 60 who undergo total hip arthroplasty under general anesthesia.

Interventions

Fascia iliaca block No therapy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who will undergo total hip arthroplasty under general anesthesia.

Exclusion criteria

Exclusion criteria: 1) Patients who are impaired in perception and difficult to undergo cognitive function tests. 2) Patients who can not complete the cognitive function tests. 3) Patients who have neurological disorders. 4) Patients who have mental illness. 5) Patients who have coagulopathy. 6) Patients who have history of cardiac surgery (open heart surgery) and brain surgery. 7) Patients who have alcoholism and drug addiction. 8) Patients who are allergic to local anesthetic. 9) Patients who judged inappropriate by research doctor.

Design outcomes

Primary

Measure	Time frame
The occurrence of post-operative delirium and post-operative cognitive dysfunction.	—

Secondary

Measure	Time frame
intra-operative opioid dose intraoperative Patient Status Index (PSI) and Spectral Edge Freguency (SEF), Surpression Rate (SR), Local Oximetry (rSO 2) postoperative pain level on Day1 and Day 2 Frequency of use of PCA use of auxiliary analgesics occurrence of side effects by opioid (nausea / vomiting, dizziness, respiratory depression etc)	—

Countries

Japan

Contacts

Public ContactMaiko Hosokawa

Showa university Department of Anesthesiology

maiko-hskw@med.showa-u.ac.jp03-3784-8575

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026