Healthy adults
Conditions
Interventions
Carrot juice (200 mL/day for 8 weeks)
Placebo(200 mL/day for 8 weeks)
Sponsors
Others
CPCC Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Healthy Japanese Subjects 2) Subjects who notice themselves as they are mild/moderate perennial allergic rhinitis. 3) Subjects who have positive results on serum allergen-specific IgE against house dust or mites. 4) Subjects who are judged suitable for this study by principal investigator.
Exclusion criteria
Exclusion criteria: 1) Subjects who will be treated or take medicine for perennial allergic rhinitis during this study period. 2) Subjects who planning some treatment during this study period. 3) Subjects who intake the medicines, the foods for specified health uses and/or the health foods that are concerned their influence to test results. 4) Pregnant or expected pregnant, planning pregnant during this study period and lactating women 5) Subjects who have current medical history of serious disease. 6) Subjects who have previous medical history of serious disease and be judged unsuitable for this study. 7) Subjects who take medicines such as anti-histamine and anti-allergy. 8) Subjects who cannot take test food and record diary as instructions. 9) Subjects who habitually consume higher amount of alcohol ( > 60 g alcohol/day) 10) Subjects who have non-allergic rhinitis 11) Subjects who cannot eat carrot 12) Subjects with risk of allergy regarding to this study 13) Subjects who are participating in the other clinical tests. Subjects who participated in the other clinical tests within 2-months prior to this study and/or who plan to participate in the other clinical tests. 14) Subjects who donated over 200mL blood and/or blood components within the last one month to this study. (15) Subjects who donated over 400mL blood and/or blood components within the last three month to this study. (16) Females who donated over 400mL blood and/or blood components within the last four month to this study. (17) Males who will be collected over 1200mL blood and/or blood components, when the sampling amounts within the last twelve month are adding to the planned sampling amounts of this study. (18) Females who will be collected over 800mL blood and/or blood components when, the sampling amounts within the last twelve month are adding to the planned sampling amounts of this study. 19) Subjects who are judged unsuitable for this study by principal investigator and doctors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nasal symptom score (Record score using a 5 point scale and Japan Rhinoconjunctivitis Quality of Life Questionnaire(JRQLQ)) before and 2, 4, 6, 8 weeks after the intervention with carrot juice or placebo. | — |
Secondary
| Measure | Time frame |
|---|---|
| Ocular symptom score, QOL score(JRQLQ), non-specific IgE, Allergen-specific IgE, eosinophil count in nasal discharge, White blood cell differentiation count, Serum carotenoid concentrations | — |
Countries
Japan
Contacts
Public ContactSuguru Fujiwara
CPCC Co., Ltd. Clinical Research Planning Department
Outcome results
None listed