Coronary Plaque Monitoring using Coronary CT Angiography: Variability of CT Scanners and Observers

Coronary Plaque Monitoring using Coronary CT Angiography: Variability of CT Scanners and Observers - Coronary Plaque Monitoring using Coronary CT Angiography

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000034030

Enrollment

Registered

2018-10-05

Start date

2018-10-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery stenosis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Provide informed consent 2. CAD with an anatomical stenosis 30% or more, diagnosed on coronary CT angiography 3. stable symptom

Exclusion criteria

Exclusion criteria: 1. Age of <20 or >=85 yrs. 2. Need for early revascularization 3. History of coronary stent or bypass 4. Agatston score >1000 5. Renal dysfunction (eGFR <45 mg/dl/1.73m2) 6. Estimated radiation exposure of 15 mSv or more within 1 yr. at the time of registration. 7. Contraindication for iodine contrast medium 8. Suspected pregnancy

Design outcomes

Primary

Measure	Time frame
The primary endpoints of this study are, 1. The sample size required by coronary CT angiography to show a clinical change with 90% power and an a error of .05. based on intraclass correlation coefficients. 2. Variability and agreement of CT findings of vulnerable plaque.	—

Secondary

Measure	Time frame
The secondary endpoints of this study are, 1. Radiation dose for coronary CTA. 2. Reproducibility of coronary calcium score 3. Reproducibility of diameter stenosis 4. Reproducibility of wall volume 5. Reproducibility of lumen volume	—

Countries

Japan

Contacts

Public ContactHidenobu Takagi

Iwate Medical University Department of Radiology

hdnb69tkg@gmail.com019-651-5111

Outcome results