analysis of endoscopic brush samples identified mucosa associated dysbiosis and the expression of tight junction protein in functional dyspepsia.

analysis of endoscopic brush samples identified mucosa associated dysbiosis and the expression of tight junction protein in functional dyspepsia. - mucosa associated dysbiosis and the expression of tight junction protein in functional dyspepsia.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000033978

Enrollment

Registered

2018-09-10

Start date

2017-05-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Functional dyspepsia(FD)

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: criteria of Rome4 in FD without infection of Hericobater pyroli

Exclusion criteria

Exclusion criteria: Additional exclusion criteria were as follows: administration of antibiotics, corticosteroids, immunosuppressants, and acid suppressing agents proton pump inhibitors (PPIs) and histamine-type 2 receptor blockers (H2 blockers) within the past 1 month, and a history of underlying malignant diseases.Patients with other factors that could affect intestinal motility or gut microbiota, as evaluated by researchers, were also ineligible.

Design outcomes

Primary

Measure	Time frame
The characteristics of the gastrointestinal MAM in FD.	—

Countries

Japan

Contacts

Public ContactAkifumi Fukui

North Medical Center Kyoto Prefectural University of Medicine Department of Molecular Gastroenterology and Hepatology

afukui@koto.kpu-m.ac.jp0772463371

Outcome results