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A phase I trial examining the safety of major left lung resection with left atrial appendectomy for left lung cancer patients with atrial fibrillation

A phase I trial examining the safety of major left lung resection with left atrial appendectomy for left lung cancer patients with atrial fibrillation - A phase I trial examining the safety of major left lung resection with left atrial appendectomy

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000033974
Enrollment
5
Registered
2018-09-03
Start date
2019-03-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

malignant tumor of the lung atrial fibrillation

Interventions

None listed

Sponsors

Niigata University Graduate School of Medical and Dental Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patients who are scheduled for surgery for left malignant pulmonary tumor (suspected or confirmed) 2.surgical procedure: segmentectomy >= 3.non-valvular atrial fibrillation 4.20 years <= 5.ECOG performance status of 0 or 1 6. No following surgical history i) left thoracotomy ii) left thoracoscopic resection of lung, esophagus, and mediastinum (except for thoracoscopic resection of bullae) iii) Heart and great vessel surgery (except for thoracic endovascular aortic repair) 7.Written informed consent

Exclusion criteria

Exclusion criteria: 1.Active infection requiring systemic therapy 2. Female during pregnancy, within 28 days of postparturition, or during lactation and male expecting partner's pregnancy 3.Severe psychological disorder 4.History of myocardial infarction or attack of angina pectoris within the past 3 weeks 5.Uncontrollable valvular disease, dilated cardiomyopathy, and hypertrophic cardiomyopathy 6.Interstitial pneumonitis 7.thrombus in left atrial appendage 8.No radiotherapy at the site of operation 9. a participating surgeon judged that the patient was not appropriate candidate for the study

Design outcomes

Primary

MeasureTime frame
Adverse events rate

Secondary

MeasureTime frame
Operative time Bleeding volume length of drainage tube placement length of hospital stay

Countries

Japan

Contacts

Public ContactTatsuya Goto

Niigata University Graduate School of Medical and Dental Sciences Division of Thoracic and Cardiovascular Surgery

gotou-akt@umin.ac.jp025-227-2243

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026