Short term impact of tolvaptan withdrawal in patients with ADPKD.

Short term impact of tolvaptan withdrawal in patients with ADPKD. - Short term impact of tolvaptan withdrawal in patients with ADPKD.

Status

Recruiting

Phases

Phase 4

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000033968

Enrollment

Registered

2018-08-31

Start date

2015-08-17

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autosomal dominant polycystic kidney disease: ADPKD

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Outpatients with PKD at our hospital who participated in the domestic test of tolvaptan.

Exclusion criteria

Exclusion criteria: Patients who self-suspended hospitalization. Patients who did not obtain consent.

Design outcomes

Primary

Measure	Time frame
Change in the slope of kidney function as mesured by the reciprocal of the GFR, total kidney volume.	—

Secondary

Measure	Time frame
The slope of change in serum creatinine level, sodium level, gravity of urine.	—

Countries

Japan

Contacts

Public ContactNaoko Shimoda

Nippon Medial School Hospital Department of Nephrology

shimodana05@nms.ac.jp0338222131

Outcome results