None (Healthy adult)
Conditions
Interventions
Ingestion of Bifidobacterium-containing food for 12 consecutive weeks
Ingestion of placebo for 12 consecutive weeks
Sponsors
TTC Co., Ltd
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Healthy male and female aged from 50 to 69 2)Subjects with self-awareness of forgetfulness 3)Subjects with inferior scores of cognitive function tests
Exclusion criteria
Exclusion criteria: 1)Subjects who are difficult to discriminate color 2)Subjects with bad eyesight, or are diagnosed with amblyopia or blindness 3)Subjects with bad hearing, or are diagnosed with hearing loss or permanent hearing loss 4)Subjects with history of cranial nerve disease 5)Subjects who are under treatment of cognitive functions, or are prescribed with medicine for them 6)Subjects who are suspected dementia 7)Subjects who have depressive symptoms, or who have been diagnosed as depressive disorder 8)Subjects who are under hormone treatment or who have been diagnosed as menopausal symptoms 9) Subjects who have a pain or disease that troubles with keystrokes 10)Subjects who have some irregular schedules during the study, due to night work or something 11)Subjects who drink much alcohol 12)Subjects who smoke, or quit smoking within one year before pre-inspection 13)Subjects who have done the same cognitive function test within one yea4 14)Subjects who continuously take medicine, health foods related to cognitive functions and/or rich in lactic acid bacteria 15)Subjects who was given or donated 200 ml or 400 ml whole blood within three months before pre-inspection 16)Subjects who participated in other study within one month before pre-inspection, or are going to participate in other study during the study 17)Subjects who have a disease which needs regular medication, or have a history of the disease 18)Subjects who are judged as unsuitable for the study by investigator because of clinical test, anthropometric test and physical examination in pre-inspection 19)Subjects who have possibilities for emerging allergy onset related to the study 20)Subjects who are pregnant or lactating, or plan to become pregnant or lactate during the study 21)Subjects who are judged as unsuitable for the study because of lifestyle questionnaire 22)Subjects who are judged as unsuitable for the study by investigator for other reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitrax (memory) at 12 week ingestion | — |
Secondary
| Measure | Time frame |
|---|---|
| Cognitrax (others) and BDNF at 12 week ingestion | — |
Countries
Japan
Contacts
Public ContactTakashi Nakagawa
TTC Co., Ltd. Clinical Research Planning Department
Outcome results
None listed