Effect of cooling sensation induced by olfactory stimulation by L-menthol on dyspnea during inspiratory resistive load breathing in healthy, elderly and COPD people.

Effect of cooling sensation induced by olfactory stimulation by L-menthol on dyspnea during inspiratory resistive load breathing in healthy, elderly and COPD people. - Effect of Menthol on Dyspnea in COPD (MeDCOPD STUDY)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000033822

Enrollment

180

Registered

2018-09-02

Start date

2018-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy, elderly and COPD people.

Interventions

olfactory stimulation by l-menthol placebo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: healthy college students, elderly people (from 60 to 85 years old) without exclusion criteria and stable COPD patients (from 60 to 85 years old) at Terada internal medicine and respiration .

Exclusion criteria

Exclusion criteria: The history of cardiopulmonary diseases, rhinitis, seasonal allergy, sinusitis, myocardial infarction, pneumothorax, exacerbations within 8 weeks and common cold within 4 weeks. If participants feels coughing or uncomfortable with perfume or smell.

Design outcomes

Primary

Measure	Time frame
Dyspnea by modified Borg scale. Japanese version of multidimensional dyspnea profile,	—

Countries

Japan

Contacts

Public ContactMasashi Kanezaki

Himeji Dokkyo University Department of Physical Therapy, Faculty of Health Care Sciences.

kmasashi@gm.himeji-du.ac.jp0782236732

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026