congenital anomaly
Conditions
Interventions
After starting feeding, 1 kg of LKM 512 bifidus per day and taking it until discharge date (14 - 28 days)
Of the newborn hospital admitted to our hospital (including cases transferred from other hos
Sponsors
Juntendo University School of Medicine
Kyodo Milk Industry Co. Ltd
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Of the newborn hospital admitted to our hospital (including cases transferred from other hospital births), surgical cases, non surgical cases, normal newborns are examined 1) From Committee Approval date to born on March 1, 2019 2) The presence or absence of serious complication malformation (chromosomal abnormality, complex heart disease) is not required 3) Whether actively treated, palliative or restrictive treatment was selected
Exclusion criteria
Exclusion criteria: 1) The patient was considered prenatally diagnosed as requiring surgery but was aborted or in utero fetal death. 2) Patients who underwent surgery after 28 days of age
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cytokines in blood (IL6, IL10, IL12, IL18, IFNg), IgG, IgA, IgE are measured. DNA analysis of intestinal microflora in feces with next generation sequencer. For each item, compare with neonatal surgery case / non-surgical case. Blood and fecal samples should be taken at the following schedule. (Surgery case: at birth, immediately before surgery, immediately after surgery, 1st day after surgery, 3rd day, 7th day Non-surgical case: at birth, 1st day after birth, 3rd day, 7th day) We will examine the correlation between postoperative clinical course and the above results. | — |
Countries
Japan
Contacts
Public ContactMANABU OKAWADA
Juntendo University School of Medicine Pediatric General & Urogenital Surgery
Outcome results
None listed