venous thromboembolism (VTE)
Conditions
Interventions
Standard physiotherapy groups such as intermittent pneumatic compression (IPC), wearing elastic stockings and early exit and active exercise
A group using a combination of standard physical therapy an
Sponsors
Hyogo college of Medicine
National Cerebral and Cardiovascular Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with colorectal cancer 2. Patients over 40 years old 3. Patients scheduled to undergo radical surgery by laparoscopy 4. Patient who can acquire document consent from the person himself or his substitute
Exclusion criteria
Exclusion criteria: 1. Patient who is bleeding 2. Patients with complications that may cause bleeding (excluding diseases subject to surgery) 3. Patient who does not retain main organ function (measured within 42 days before registration date by blood test) 4. Patients whose history of hypersensitivity to the test drug components, heparin, heparin derivatives (low molecular weight heparin, etc.) has been confirmed 5. Patients with a history of cerebral hemorrhage 6. Patients who underwent surgery of the central nervous system (brain, spine) or ophthalmic surgery (excluding cataract surgery) within 3 months before the trial registration 7. Patients with contrast medium allergy 8. Patients with a history of heparin-induced thrombocytopenia (HIT) 9. Patients who underwent major orthopedic surgery, abdominal surgery or cardiovascular surgery on the lower extremities within 3 months prior to registration of this study 10. In this study, patients who received the following combination prohibited drug within one week before registration (Heparin, low molecular weight heparin, danaparoid, antithrombin agent, warfarin, thrombolytic agent, antiplatelet drug) 11. Patients requiring heparin substitution during the perioperative period 12. In preoperative examination, patients diagnosed with VTE 13. Patients with a history of arterial thromboembolism (including cerebral infarction and myocardial infarction) 14. Patients with drug dependence or alcoholism 15. Patients who are planning other surgical operations during the study period 16. Patients who are pregnant or have a possibility of pregnancy 17. Patients participating in other clinical trials at the same time as this study (except observational research) 18. Other patients who are judged inappropriate by the examination responsible doctor or the test sharing doctor as the examination subject
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Presence or absence of expression of VTE after colon resection | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Presence or absence of Major bleeding 2. Presence or absence of Minor bleeding 3. Measurement result of anti-PF4 / heparin antibody | — |
Countries
Japan
Contacts
Public ContactJihyung Song
Hyogo College of Medicine Division of Lower gastrointestinal Surgery
Outcome results
None listed