A multicenter prospective study of risk factors associated with medication-related osteonecrosis of the jaw after tooth extraction in cancer patients receiving intravenous bisphosphonate or denosumab therapy

A multicenter prospective study of risk factors associated with medication-related osteonecrosis of the jaw after tooth extraction in cancer patients receiving intravenous bisphosphonate or denosumab therapy - A prospective study of MRONJ after tooth extraction in cancer patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000033743

Enrollment

500

Registered

2020-04-01

Start date

2019-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer patients receiving high-dose bone-modifying agents who tooth extraction were performed

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who could be investigated treatment method and prognosis Cancer patients receiving high-dose bone-modifying agents who tooth extraction were performed Patients who are over 20 years of age

Exclusion criteria

Exclusion criteria: Patients who reject to participate this study

Design outcomes

Primary

Measure	Time frame
The incident rate of MRONJ at 2 months after tooth extraction	—

Countries

Japan

Contacts

Public ContactTakumi Hasegawa

Kobe University Graduate School of Medicine Department of Oral and Maxillofacial Surgery

hasetaku@med.kobe-u.ac.jp078-382-6213

Outcome results