Therapeutic effect on disodium pamidronate administration to diffuse sclerosing mandible osteomyelitis

Therapeutic effect on disodium pamidronate administration to diffuse sclerosing mandible osteomyelitis - On the effect of disodium pamidronate on diffuse curable mandibular osteomyelitis

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000033725

Enrollment

Registered

2020-10-01

Start date

2020-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diffuse sclerosing osteomyelitis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who underwent dental oral surgery at Osaka Medical University Hospital and underwent treatment with diamantane pamidronate for DSO

Exclusion criteria

Exclusion criteria: Patients who did not obtain consent to this study

Design outcomes

Primary

Measure	Time frame
Dissolve pamidronate disodium in 500ml of raw diet for patients with diffuse osteomyelitis and take IV infusion over 4 hours. The number of doses is only once, but when symptoms such as pain are observed, re-administration is performed at intervals of 3 to 6 months.Comparison of changes in jaw bone due to clinical symptoms and image findings before and after administration of disodium pamidronate, and evaluate the improvement effect of diamid pamidronate on DSO	—

Measure

Time frame

Dissolve pamidronate disodium in 500ml of raw diet for patients with diffuse osteomyelitis and take IV infusion over 4 hours. The number of doses is only once, but when symptoms such as pain are observed, re-administration is performed at intervals of 3 to 6 months.Comparison of changes in jaw bone due to clinical symptoms and image findings before and after administration of disodium pamidronate, and evaluate the improvement effect of diamid pamidronate on DSO

—

Countries

Japan

Contacts

Public ContactNakajima Yoichiro

Osaka Medical and Pharmaceutical University Department of Oral and Maxillofacial Surgery

n4160@ompu.ac.jp0726831221

Outcome results