Diagnostic accuracy of MRI in lateral pelvic lymph node metastasis of rectal cancer

Diagnostic accuracy of MRI in lateral pelvic lymph node metastasis of rectal cancer - Diagnostic accuracy of MRI in lateral pelvic lymph node metastasis of rectal cancer

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000033702

Enrollment

272

Registered

2018-08-09

Start date

2017-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rectal cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) A case with primary rectal cancer is scheduled for TME and LLND 2) A case with histologically confirmed adenocarcinoma 3) Informed consent is obtained for participation in the study 4) Regarding Step 1, the postoperative registration is permissible.

Exclusion criteria

Exclusion criteria: 1) A case with a contraindication for MRI, such as use of artificial devices (e.g., cardiac pacemaker) 2) A case wherein assessing the status of LLN metastasis on MRI imaging is difficult because of intrapelvic artifacts 3) A case with an intrapelvic neoplasm, barring colorectal cancer, such as prostate cancer, bladder cancer, uterine cancer, and ovarian cancer. 4) A patient who is deemed to be inappropriate for study enrolment by the principal investigator or researcher

Design outcomes

Primary

Measure	Time frame
The diagnostic sensitivity of LLN metastasis on MRI	—

Secondary

Measure	Time frame
1. The specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of the diagnosis of LLN metastasis on MRI. 2. The coincidence ratio of morphologic change assessments among the observers 3. The correlation between extramural venous invasion (EMVI) of the primary lesion and LLN metastasis 4. The influence of neoadjuvant therapy for the diagnosis of LLN metastasis on MRI 5. The correlation between the LLN metastasis diagnosed by MRI and the patients' prognosis 6. The difference between the diagnostic accuracy of LLN metastasis on MRI and CT	—

Measure

Time frame

1. The specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of the diagnosis of LLN metastasis on MRI. 2. The coincidence ratio of morphologic change assessments among the observers 3. The correlation between extramural venous invasion (EMVI) of the primary lesion and LLN metastasis 4. The influence of neoadjuvant therapy for the diagnosis of LLN metastasis on MRI 5. The correlation between the LLN metastasis diagnosed by MRI and the patients' prognosis 6. The difference between the diagnostic accuracy of LLN metastasis on MRI and CT

—

Countries

Japan,Europe

Contacts

Public ContactKazushie Kawai

The University of Tokyo Department of Surgical Oncology

kz-kawai@mvd.biglobe.ne.jp+81-3-3815-5411

Outcome results