Healthy adults
Conditions
Interventions
Apply test product A to the left palm and medial forearm, and placebo to the right palm and medial forearm, twice a day for 7 days in the first half investigation. After washout period of 3 weeks, app
Sponsors
Kao Corporation
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1.Informed consent provided 2.Able to follow the instruction of the study team
Exclusion criteria
Exclusion criteria: 1.Subjects with injury such as wound or eczema on hands or forearms 2.Subjects with severe sunburn on hands or forearms 3.Subjects with atopic dermatitis or contact skin hypersensitivity 4.Subjects who need a routine visit to a clinic or regular medication 5.Subjects who participate in other research or treatment with physical loads that affect this test 6.Subjects deemed inappropriate to participate in this study by the principle investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Indices with regard to skin barrier; expression level of antimicrobial peptide and bactericidal action | — |
Secondary
| Measure | Time frame |
|---|---|
| Indices with regard to skin conditions; skin physiological parameters such as skin conductance and TEWL | — |
Countries
Japan
Contacts
Public ContactShigeyuki Ono
Kao Corporation Biological Science Research
Outcome results
None listed