Retrospective observational study on adjuvant chemotherapy after advanced lower rectal cancer surgery

Retrospective observational study on adjuvant chemotherapy after advanced lower rectal cancer surgery - Retrospective observational study on adjuvant chemotherapy after advanced lower rectal cancer surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000033688

Enrollment

1000

Registered

2018-08-09

Start date

2015-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Advanced rectal cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Patient who underwnet rectal cancer surgery between 2008 and 2012 2)Tumor distal edge was located below peritoneal reflection 3)Pathological T3/T4 or N1/N2/N3 4)No distant metastasis

Exclusion criteria

Exclusion criteria: 1)Patient who performed preoperative treatment (chemotherapy, radiotherapy, chemoradiotherapy) 2)Petients who are considered to be inappropriate for this trial by doctor

Design outcomes

Primary

Measure	Time frame
Implementation rate of adjuvant chemotherapy	—

Secondary

Measure	Time frame
1)Regimen, period of administration, total dose of adjuvant chemotherapy 2)Adverse event of adjuvant chemotherapy 3)Reasons for not performingen adjuvant chemotherapy after surgery 4)Relapse-free survival, overall survival, local recurrence rate 5)Risk factors for local recurrence 6)Risk factors for anastomatic leakage 7)Risk factors for postoperative urinary disorder	—

Countries

Japan

Contacts

Public ContactKazuya Nakagawa

Yokohama City University Medical Center Department of Surgery, Gastroenterological Center

nakagawakazuya0827@yahoo.co.jp045-261-5656

Outcome results