Hemophilia, HIV infection, neurocognitive disorder
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1)HIV-infected hemophilia, (2)Older than 20 years old, (3)Written informed consent
Exclusion criteria
Exclusion criteria: (1)Active AIDS-defining disease (2)Congenital developmental retardation (3)Definitive diagnosis of following diseases a. Mental disorder: major depressive disorder, schizophrenia b. Alzheimer's disease, Frontotemporallobar degeneration, Lewy-body disease, Vascular disease, Traumatic brain injury, Prion disease, Parkinson's disease, Huntington's disease c. Another functional neurocognitive disorder d. Illegal substance use e. Severe alcoholism f. Endocrine disorder: hypothyroidism, Wernicke encephalopathy, Vitamin B12 deficiency g. Current treatment or sever sequelae of CNS opportunistic infections h. Symptoms of a current, active infection a body temperature of >38.5 at the time of recruitment (4)Experience of neuropsychiatric test within past 1 year (5)Other inappropriate condition for neuropsychiatric test
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The prevalence and severity of neurocognitive disorder in HIV-infected hemophilia | — |
Countries
Japan
Contacts
Hokkaido University Hospital HIV infection Medical Support Center