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Influence of oral ingestion of hydrogen containing jelly on periodontal tissue

Influence of oral ingestion of hydrogen containing jelly on periodontal tissue - Influence of oral ingestion of hydrogen containing jelly on periodontal tissue

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000033592
Enrollment
20
Registered
2018-09-18
Start date
2018-09-19
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gingivitis

Interventions

Hydrogen-containing jelly is swallowed after chewing for 10 seconds three times a day (after every meal) for 14 consecutive days. Hydrogen-free jelly is swallowed after chewing for 10 seconds three ti

Sponsors

Department of Preventive Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Lead Sponsor
Department of oral biochemistry, Asahi University Graduate School of Dentistry.
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Persons with inflammation in the maxillary anterior periodontal tissue

Exclusion criteria

Exclusion criteria: Persons who took antibiotics, anti-inflammatory drugs, antiallergic drugs within the past two weeks Smoker Women who are pregnant or are likely to become pregnant Lactating women

Design outcomes

Primary

MeasureTime frame
percentage of sites of bleeding on probing

Secondary

MeasureTime frame
probing pocket depth clinical attachement level periodontal inflamed surface area: PISA plaque control record: PCR oxidative stress (d-ROMs) and antioxidant capacity (OXY-adsorbent test) of serum oxidative stress (8-OHdG) and lactate dehydrogenase of unstimulated saliva cytokines (IL-1 beta, IL-6, IL-10, IL-17, and TNF-alpha) levels of gingival crevicular fluid

Countries

Japan

Contacts

Public ContactManabu Morita

Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Department of Preventive Dentistry

mmorita@md.okayama-u.ac.jp086-235-6712

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026