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A validation study of biomarkers to predict responders to non-pharmacological multimodal program for advanced cancers

A validation study of biomarkers to predict responders to non-pharmacological multimodal program for advanced cancers - NEXTAC-Three

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000033574
Enrollment
100
Registered
2019-03-31
Start date
2019-03-31
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-small-cell lung and pancreatic cancer

Interventions

1. nutritional couseling 2. home-based exercise intervention 3. physical activity intervention

Sponsors

Department of Respirology, Kyoto Prefectual University of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) >=70 years old and ECOG-PS 0-2 2) newly diagnosed NSCLC/pancreatic cancer in stage III, IV, or post-operative recurrence. 3) They are planned to receive the first-line systemic chemotherapy 4) Having written informed consent 5) More than 3 months of survival was expected

Exclusion criteria

Exclusion criteria: 1) Having disabilities according to the modified KATZ index 2) Having high risks for safe physical assessments and interventions (e.g. Unstable cardiac diseases, Severely symptomatic brain or bone mets, severe phyciatric disease, etc) 3) Having difficulties in swallowing, digesting, and absorbing food

Design outcomes

Primary

MeasureTime frame
Positive predictive value

Secondary

MeasureTime frame
Sensitivity Specificity Negative predictive value

Countries

Japan

Contacts

Public ContactTateaki Naito

Shizuoka Cancer Center Division of thoracic oncology

t.naito@scchr.jp055-989-5222

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026