Study on the detection of EGFR mutation using the high sensitive PCR method in lung cancer

Study on the detection of EGFR mutation using the high sensitive PCR method in lung cancer - Study on the detection of EGFR mutation

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000033567

Enrollment

Registered

2018-07-31

Start date

2013-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1)advanced or recurrent NSCLC harboring common EGFR mutations (exon 19 deletions, and the L858R mutation in exon 21) confirmed by the Scorpion Amplified Refractory Mutation System (ARMS) method; (2) prior to the start of EGFR-TKI treatment or disease progression after EGFR-TKI treatment; (3) allowing the collection and genomic analysis of blood samples (20 mL); (4) able to provide written informed consent.

Exclusion criteria

Exclusion criteria: None

Design outcomes

Primary

Measure	Time frame
Detect the exon 19 deletion, the L858R mutation in EGFR exon 21 and T790M mutation in EGFR exon 20	—

Countries

Japan

Contacts

Public ContactHirotsugu Kenmotsu

Shizuoka Cancer Center Division of Thoracic Oncology

h.kenmotsu@scchr.jp0559895222

Outcome results